2BIO035 Bioprocess Technology

    • Number of credits
      5
    • Teaching semester
      2023 Spring
    • Language of instruction
      English
    • Campus
      Hamar
    • Required prerequisite knowledge

      None

Course content

Content

  • production of biologicals in the bioprocess/ biopharmaceutical industry
  • fermentation technology
  • microbial and mammalian cell cultures
  • genetic engineering; cloning methods, vector systems, recombinant protein production
  • protein isolation and separation methods; centrifugation, solubility, chromatography and membrane separations
  • process economy considerations
  • structured experimental approuch by Design of Experiments

Learning Outcome

Upon successful completion of the course, the student will have achieved the following learning outcomes: 

Knowledge

Upon successful completion of the course, the student will have achieved the following learning outcomes: 

Skills

The student  

  • understands how lab scale methods transform into large scale, and how main unit operations in downstream processing (centrifugation, filtration, and chromatography) function
  • has advanced understanding of design of expression vector systems for protein production
  • can perform experimental procedures for recovery and purification of a protein and evaluate the outcome
General competence

The student 

  • understands how and why bioprocessing is employed to increase value of the feed stream
  • has deeper knowledge of the main workflow and logic behind bioprocessing both in lab and industrial scale, and able to identify unit operations
  • can analyze how genetic engineering is used to harness cell systems for protein production
Teaching and working methods

Organization and Methods of Instruction

  • lectures ca. 20 hours
  • lab exercise - two days
  • in-class group activities
Required coursework

Requirements necessary to take the exam

  • 100% attendance at the preparatory lab lecture
  • 100% participation at laboratory exercise
  • one written individual laboratory report from lab must be passed
Form of assessment

Assessment

  • 4-hour individual written school exam 

 

Assessments
Form of assessmentGrading scaleGroupingDuration of assessmentSupport materialsProportionComment
Written assignment
ECTS - A-F
Individual
  • Kalkulator
60 %
Written examination with invigilation
ECTS - A-F
Individual
4 Hour(s)
  • Kalkulator
40 %

Reading list

Faculty
Faculty of Applied Ecology, Agricultural Sciences and Biotechnology
Department
Department of Biotechnology