BIO4105 Bioproduction and Biorefining Technology

    • Course code
      BIO4105
    • Number of credits
      10
    • Teaching semester
      2025 Spring
    • Language of instruction
      English
    • Campus
      Hamar
    • Required prerequisite knowledge

      Microbiology, biochemistry with emphasis on enzymology/kinetics and fermentative metabolism.

Course content
  • Biomass characteristics (lignocelluloses, food waste, crop residues), analytical methods,
  • Biorefinery technologies for biomass treatment, including pulping, physical, thermal, enzymatic, and solvent extraction methods (solid-liquid, liquid-liquid)
  • Microbial conversions, including fermentation technology, reactor types, growth kinetics, mass balance, and yields
  • Downstream processing with a focus on the recovery and purification of valuable proteins and other bio-based compounds
  • Enzyme technology, process solutions, free and immobilized catalyst, reaction conditions, and kinetics
  • The lab course consists of (1) characterization of lignocellulosic biomass (hemi-/ cellulose, lignin, ash); (2) pretreatment of biomass (high-temperature processing, organosolv, autoclave); (3) analysis of pretreated streams (solids: hemi-/cellulose, lignin; liquid: sugars by HPLC); (4) enzymatic saccharification (cellulases, reaction conditions, sugar yield); (5) ethanolic fermentation (yield, gas evolution, HPLC analysis); (6) data analysis (calculation of yields and mass balances, the effect of treatments and reaction conditions).
    The course concludes with a seminar where the student groups present their results and interpretation, followed by an examination and discussion. Evaluation is pass/no pass.

Learning Outcome

Upon passing the course, students have achieved the following learning outcomes:

Knowledge

Students 

  • have thorough understanding of biological and biomass conversion processes, given the United Nations Sustainable Development Goals (#): 
    • increased resource-use efficiency and greater adoption of clean and environmentally sound technologies and industrial processes (cf. #9.4)  
    • sustainable use of natural resources (cf. #12.2 and 12.5) 
Skills

Students

  • can use the principles and applications of technologies in the bioconversion of biomasses and substrates to valuable products.
  • can analyze and evaluate different scenarios of biorefinery and biotechnological production.
  • can give oral presentations where experimental results are explained.
General competence

Students

  • can face challenges and see possibilities with valorizing biomass materials and residues for the production of biobased derivatives.
  • understand how and why bioprocessing is employed to produce biobased derivatives and biotechnology products.
  • have profound knowledge of the main workflow and logic behind bioprocessing both on lab and industrial scale and ability to identify unit operations.
Teaching and working methods
  • Lectures, approx. 30 hrs.
  • Laboratory course consisting of 6-8 of ½ days after completion of lectures
  • Excursions to relevant regional operations
  • Guest lecturers
  • In-class activities

Normally, evaluation of all courses must be carried out. Time/date and method are decided in consultation with student representatives. The course coordinator is responsible for ensuring that the evaluation is carried out.

Required coursework
  • Attendance at 100% of the scheduled introductory lab lecture.
  • Attendance at 100% of the laboratory course.
  • Attendance at 100% of scheduled seminar and assessment.
  • The laboratory course must be passed.
Assessments
Form of assessmentGrading scaleGroupingDuration of assessmentSupport materialsProportionComment
Written examination with invigilation
ECTS - A-F
Individual
4 Hour(s)
100
Form of assessment
  • 4-hour individual written school exam

Performance is assessed using a grading scale from A-F, where E is the lowest passing grade.

Faculty
Faculty of Applied Ecology, Agricultural Sciences and Biotechnology
Department
Department of Biotechnology
Area of study
Matematisk-naturvitenskapelige fag/informatikk
Programme of study
Master's Degree in Applied and Commercial Biotechnology
Course level
Second degree level (500-HN)