2BT201 Bioprocess technology

    • Number of credits
      15
    • Teaching semester
      2022 Autumn
    • Language of instruction
      English
    • Campus
      Hamar
    • Required prerequisite knowledge

      2KJ231 Biochemistry or similar (completed previously or taken concurrently).

Course content
  • introduction to fundamental bioengineering and biochemical aspects of fermentation and bioreactor use, and purification strategies in downstream processing
  • experimental design
  • fermentation: Batch, fed-batch and continuous culture, growth curve and element balances
  • growth models
  • reactor operation and control
  • separation techniques: Membrane filtration and protein chromatography
  • strategy and scale up of separation processes
  • protein electrophoresis
  • enzyme technology and immobilization: Immobilization of biocatalysts and the use of enzyme reactors
  • simple reaction kinetics, mass transport and film theory

Learning Outcome

The candidate having completed the have the following learning outcomes:

Knowledge

The Candidate has

  • understanding of the underlying principles of bioprocesses related to fermentation, downstream processing, and enzyme reactors, as well as analytical procedures
Skills

The Candidate is

  • able to analyze data for computing process performance parameters
General competence

The Candidate has

  • acquired basic competence in performing experimental procedures with fermentation, adsorption chromatography, tangential filtration and biocatalyst immobilization
Teaching and working methods
  • lectures
  • laboratory course
  • self-guided colloquiums
Required coursework

Approved 5 lab reports.

Form of assessment
  • individual portfolio (includes a mid-term test (2 hours), and two lab reports selected by the instructor), counts 40 %
  • Individual written examination, 4-hour, counts 60 %

Both parts must be passed to receive a final grade.

Assessments
Form of assessmentGrading scaleGroupingDuration of assessmentSupport materialsProportionComment
Portfolio Assessment
ECTS - A-F
Individual
40%
Written examination with invigilation
ECTS - A-F
Individual
4 Hour(s)
60%
Faculty
Faculty of Applied Ecology, Agricultural Sciences and Biotechnology
Department
Department of Biotechnology